RNA sequencing at scale.
Discover the unparalleled scalability of our multiplexed RNA-seq solutions and unleash the power of big RNA data.
What is BRB-seq?
Benefits
More samples, more data
Add more samples and replicates to your analysis for better statistics and robust results.
Diverse
sample type
From purified RNA to cells and organoids lysate, our solutions are compatible with multiple sample types.
Cost
efficient
An ultra-efficient library prep technology translates into drastic cost reductions.
High data quality
We do not compromise on data quality and provide sensitive and unbiased gene expression profiling.
Our Technology
Bulk RNA Barcoding and sequencing
The core principle of our technology is the use of highly optimized sets of barcoded primers, the BRB-seq oligos. They are used to "tag" individual RNA samples in a unique and sample-specific manner. Our oligos are optimized and validated to enable the generation of consistent, reproducible and uniform RNA sequencing data.
Massive sample multiplexing
RNA barcoding occurs at the first step of the library preparation workflow, after which, samples can be pooled and processed together in one single tube. In essence, BRB-seq provides a drastic decrease in reagents use, plastic consumption and manual operations. With BRB-seq, the more samples, the better!
Modules
Optimised, gentle but efficient lysis buffer
By combining an efficient but gentle lysis buffer, which is compatible with downstream enzymatic processing, the DRUG-seq system enables to begin library preparation directly on cell lysates without having to go through the trouble of cumbersome RNA extraction.
Products
All our products are linked by a common mission: to enable simple, fast and cost-efficient generation of "big RNA data" from diverse sample types.
MERCURIUS™
DRUG-seq library preparation kits
for Illumina® and AVITI™
RNA Extraction-free protocol
MERCURIUS™
BRB-seq library preparation kits
for Illumina® and AVITI™
RNA-seq at scale for purified RNA samples
MERCURIUS™
Plant BRB-seq library preparation kits for Illumina® and AVITI™
RNA-seq at scale for purified plant RNA samples
Unlock your screening potential with MERCURIUS™ DRUG-seq and BRB-seq
Discover the advantages compared to conventional RNA-seq
Latest News & Events
Full-length BRB-seq BETA kits are now available!
Massively multiplexed and full-length mRNA-seq from purified RNA samples.
We launched Targeted BRB-seq and DRUG-seq kits and services!
Tailor your research with targeted gene panels designed to meet your unique needs while maximizing efficiency and precision.
EACR Congress
Join us at the EACR and explore how our innovative genomic solutions can make a difference in cancer research.
SLAS Europe
Meet Alithea Genomics at the European SLAS! Discover how our RNA sequencing solutions can be used for screening and more!
Alithea Genomics is trusted by
Speak with our RNA sequencing experts
Book a one-on-one call with one of our RNA experts to discover how we can assist your next project.