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For researchers performing drug discovery, drug repurposing, toxicogenomic screens, or CRISPR screens, the end goal is often to uncover mechanisms of action, determine on- and…
The Joint Undertaking in Morphological Profiling-Cell Painting Gallery (JUMP-CP) is a large-scale, high-content imaging reference dataset created with the Cell Painting technology that assesses the…
Large-scale perturbational profiling is time and cost-intensive, so it’s crucial to compare the capabilities of different technologies to help plan and design experiments efficiently.
…Imagine if cells could attend an art class. Instead of brushes and canvases, they’d use fluorescent dyes and high-throughput microscopes to create their own masterpieces….
DRUG-seq is a cost-effective, high-throughput bulk RNA-seq library preparation method for compound screening in drug discovery and development (Ye et al., 2018; Li et al.,…
The world of crop science is evolving rapidly. New technologies are emerging that promise to revolutionize the field. One such technology is BRB-seq.
…MERCURIUS™ DRUG-seq is a rapid, cost-effective, RNA-extraction-free bulk 3’ mRNA-seq method. It provides ultra-high-throughput studies, such as drug discovery and toxicogenomic screens, with unbiased, transcriptome-wide…
RNA expression signatures are essential for understanding the molecular mechanisms underlying many biological processes and diseases. The analysis of RNA expression signatures provides information about…
The Connectivity Map is a large-scale comprehensive catalog of cellular transcriptomic signatures that represent systematic genetic or pharmacologic perturbations of many human disease cell types…
Currently, there is no efficient way to predict how the immune system will respond to COVID-19 exposure. The immune response could range from mild…
Life scientists have been using the Drosophila Melanogaster, commonly known as the fruit fly, for over a century now as a model system to study…
Tumours are very heterogeneous. Somewhat counterintuitively, this heterogeneity goes beyond the malignant cells. In fact, tumours are also made up and influenced by non-malignant cells,…
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