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Despite its widespread use, RNA-seq is still too laborious and expensive to replace RT-qPCR as the default gene expression analysis method. We anticipate that RNA-seq…
RNA sequencing (RNA-seq) provides a molecular snapshot of the cellular transcriptome, offering a treasure trove of information regarding gene regulation and expression. One of the…
The largest blood cell genotyping and transcriptomic study ever performed has shown that a much higher number of common changes in the DNA sequence affect…
A recent ground-breaking study uses a mathematical approach to measure tumor-specific total mRNA levels from mixed tumor samples. Bulk RNA-seq data from 6,664 tumor samples…
Diffuse midline gliomas: background and emerging therapies
…A recent publication has used Bulk RNA Barcoding and sequencing (BRB-seq) to investigate one of the fundamental questions of embryonic development (Liu et al., 2020).
…In 2018 The Cancer Genome Atlas (TCGA) published groundbreaking findings from the largest ‘multi-omics’ cancer study ever performed (Hoadley et al., 2018).
…In 2020, the Genotype-Tissue Expression (GTEx) Consortium published seminal findings about how sex influences tissue-specific gene expression (Oliva et al., 2020). Using large scale RNA-seq…
The cost of RNA-sequencing (RNA-seq) ranges from approximately $36.9 to $173 for a single sample in an mRNA-seq experiment. Sequencing costs have dropped significantly thanks…
DRUG-seq is a novel high-throughput, cost-effective RNA-seq method for drug discovery (Ye et al., 2018; Li et al., 2022). Researchers have used DRUG-seq and similar…
DRUG-seq, Combi-seq, and BRB-seq are three novel high-throughput transcriptomic technologies accelerating drug discovery in more disease areas than ever before. They provide unbiased, comprehensive gene…
High-throughput RNA-sequencing (RNA-seq) is the use of next generation sequencing technology to explore the transcriptome of a genome. It allows researchers to characterize and compare…
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