More samples, more data
Add more samples and replicates to your analysis for better statistics and robust results.
End
to end
From cells to data analysis, we offer a comprehensive discovery toolkit.
Cost
efficient
An ultra-efficient library prep technology translates into drastic cost reductions.
High data quality
We do not compromise on data quality and provide sensitive and unbiased gene expression profiling.
Bulk RNA Barcoding and sequencing
The core principle of our technology is the use of highly optimized sets of barcoded primers, the BRB-seq oligos. They are used to "tag" individual RNA samples in a unique and sample-specific manner. Our oligos are optimized and validated to enable the generation of consistent, reproducible and uniform RNA sequencing data.
Massive sample multiplexing
RNA barcoding occurs at the first step of the library preparation workflow, after which, samples can be pooled and processed together in one single tube. In essence, BRB-seq provides a drastic decrease in reagents use, plastic consumption and manual operations. With BRB-seq, the more samples, the better!
Custom
globin blockers
We have developed custom globin blockers that seamlessly integrate with the existing BRB-seq workflow. The resulting Blood BRB-seq is the state-of-the-art solution for blood transcriptomics studies of all sizes based on gene expression analysis.
Optimised, gentle but efficient lysis buffer
By combining an efficient but gentle lysis buffer, which is compatible with downstream enzymatic processing, the Cell Lysate BRB-seq system enables to begin library preparation directly on cell lysates, without having to go through the trouble of cumbersome RNA extraction.
Products
All our products are linked by a common mission: to enable simple, fast and cost-efficient generation of "big RNA data" from diverse sample types.
MERCURIUS™ BRB-seq library preparation kits for Illumina®
RNA-seq at scale for purified RNA samples
- 24-, 96- and 384-sample multiplexing formats
- Multiple UDIs included for smaller pool sizes
- Suitable for projects of all sizes
MERCURIUS™ Blood BRB-seq library preparation kits for Illumina®
The power of scalability with integrated globin depletion
- BRB-seq + seamless globin depletion
- Available for human and mouse blood RNA
- Validated on fresh blood and PAXgene® blood RNA samples
MERCURIUS™ Cell Lysate BRB-seq kits for Illumina®
RNA Extraction-free protocol
- Bypasses RNA extraction
- Lysis buffer compatible with 2D cultures
- Ideal for large-scale screening projects
MERCURIUS™ Organoid Lysate BRB-seq kits for Illumina®
RNA Extraction-free protocol
- Bypasses RNA extraction
- Lysis buffer compatible with organoids and spheroids
- Ideal for large-scale screening projects
Services
Not ready to use our kits?
No problem, send us your samples and we will generate BRB-seq data for you! Thanks to BRB-seq our service is the most cost-efficient and rapid solution on the market.
Alithea Genomics is trusted by
Take your next project to new heights with more replicates and more conditions.
