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RNA sequencing at scale.

Discover the unparalleled scalability of our multiplexed RNA-seq solutions and unleash the power of big RNA data.

What is BRB-seq?

Benefits

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More samples, more data

Add more samples and replicates to your analysis for better statistics and robust results.

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Diverse
sample type

From purified RNA to cells and organoids lysate, our solutions are compatible with multiple sample types.

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Cost
efficient

An ultra-efficient library prep technology translates into drastic cost reductions.

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High data quality

We do not compromise on data quality and provide sensitive and unbiased gene expression profiling.

Our Technology

Bulk RNA Barcoding and sequencing

The core principle of our technology is the use of highly optimized sets of barcoded primers, the BRB-seq oligos. They are used to "tag" individual RNA samples in a unique and sample-specific manner. Our oligos are optimized and validated to enable the generation of consistent, reproducible and uniform RNA sequencing data.

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Massive sample multiplexing

RNA barcoding occurs at the first step of the library preparation workflow, after which, samples can be pooled and processed together in one single tube. In essence, BRB-seq provides a drastic decrease in reagents use, plastic consumption and manual operations. With BRB-seq, the more samples, the better!

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Modules

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Custom
globin blockers

We have developed custom globin blockers that seamlessly integrate with the existing BRB-seq workflow. The resulting Blood BRB-seq is the state-of-the-art solution for blood transcriptomics studies of all sizes based on gene expression analysis.

Blood BRB-seq
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Optimised, gentle but efficient lysis buffer

By combining an efficient but gentle lysis buffer, which is compatible with downstream enzymatic processing, the DRUG-seq system enables to begin library preparation directly on cell lysates without having to go through the trouble of cumbersome RNA extraction.

DRUG-seq

Products

All our products are linked by a common mission: to enable simple, fast and cost-efficient generation of "big RNA data" from diverse sample types.

Services

Not ready to use our kits?

No problem, send us your samples and we will generate data for you! Thanks to BRB-seq and DRUG-seq, our service is the most cost-efficient and rapid solution on the market.

Discover our services
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Unlock your screening potential with MERCURIUS™ DRUG-seq and BRB-seq

Discover the advantages compared to conventional RNA-seq

Latest News & Events

We officially launched the FFPE-seq service!
ASHG 2023
We doubled the lysis buffer volume!
Plant BRB-seq is NOW available!

Alithea Genomics is trusted by

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Speak with our RNA sequencing experts

Book a one-on-one call with one of our RNA experts to discover how we can assist your next project.