EARLY-ACCESS
MERCURIUS™
Total DRUG-seq service
Massively multiplexed and total RNA-seq directly on cell lysates - no need for prior RNA extraction. Ultra-scalable, total RNA-seq for transcriptomic profiling and target discovery.
- Ideal for transcriptomic profiling and target validation
- Robust results empower faster, data-rich decision-making in the drug discovery pipeline.
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- Multiplexed
full-length
RNA-seq - Full-length RNA-seq library prep, 96 or 384 samples in a single tube. For both coding and non-coding RNAs.
- Full-length transcript coverage
- From differential gene expression to transcript variants, alternative splicing, or fusion genes.
- No RNA
extraction
needed - From frozen cells directly into library prep.
- Improved
protocol - Without pre-amplification, leading to higher mapping and gene detection rates.
- Fast
turnaround
times - From samples to data in as little as three weeks.
MERCURIUSTM
Total DRUG-seq service
The MERCURIUS™ Total DRUG-seq service offers a convenient and streamlined solution for full-length RNA transcriptomics projects of any size.
As part of the Total DRUG-seq service, our clients simply need to deliver to us their 96- or 384-well plates containing frozen cells.
Upon receipt, our team will start processing the plates the same week and return results in as little as three weeks.
During the process, we always keep clients informed at defined checkpoints so that we can decide together how to best proceed to the next steps.
Next-generation sequencing and data pre-processing (including alignment to the genome of choice) are part of our standard service as well. As a result, we provide our clients raw data, sequencing and alignment reports, and gene count matrices which can be used for downstream gene expression analysis.
Optional downstream differential gene expression analysis are also available upon request.
How it works
Step 1
Step 2
Step 3
Client ships samples to Alithea
Step 4
MERCURIUS™ Total DRUG-seq library preparation
2 days
Step 5
Library QC - Client Checkpoint
(Qubit, Fragment analyzer, shallow sequencing)
1 week
Step 6
Deep sequencing
1 week
Step 7
Step 8
Data
FAQs
Relevant publications
Explore the latest, relevant publications in the industry to learn more about our technologies.
Want to do Total DRUG-seq in-house?
Our Total DRUG-seq kits combine the full-length total RNA-seq with massive sample multiplexing and RNA extraction-free while providing the most cost-effective solution.
Experience sample to sequencing-ready library in one day.