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2025
  • FLASH-seq, Single-cell FLASH-seq

Local niche-derived immunosuppressive CXCR2+ cells impair antiviral immunity.

Akisawa Satomi, Riho Saito, Tadahaya Mizuno, Hiroki Sugishita, Hideki Ukai, Shigeyuki Shichino, Masashi Yanagisawa, Kouji Matsushima, Yukiko Gotoh, Tomohiko Okazaki.
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2025
  • FLASH-seq, Single-cell FLASH-seq

Molecular determinants of brain-resident CD8+ T cell formation and function. 

Tarek Elmzzahi, Chun-Hsi Su, Mehrnoush Hadaddzadeh Shakiba, Doaa Hamada, DaryaMalko, Maren Koehne, Aleksej Frolov, Teisha Mason, Yuanfang Li, Rebekka Scholz, Collins Osei-Sarpong, Leonie Heyden, Jonas Schulte-Schrepping, Lorenzo Bonaguro, Kristian Haendler, Vassiliki Boussiotis, Annett Halle, Elena De Domenico, Daniel HDGray, Martin Fuhrmann, Zeinab Abdullah, Axel Kallies, Kevin Man, Marc D. Beyer.
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2025
  • Blood BRB-seq, BRB-seq

BioSkel – Towards a Framework for OMICS Applications.

Valentin Beauvais, Clémence Couton Nicolò Tonci, Sébastien, Limet, Lucile Mollet,  Thierry Prazuck and Sophie Robert.
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2025
  • 3' BRB-seq, BRB-seq

MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes.

Wu, C., Wang, T., Ghosh, A. et al.
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2025
  • 3' BRB-seq, BRB-seq

Spermidine Reproduces the Anti-Inflammatory Effects of Intermittent Fasting and Prevents Urate and Calcium Pyrophosphate Crystal-Induced Inflammation.

Pham, C.N., Castelli, F., Finet, F., Leroy, C., Chollet, C., Chirayath, T.W., Moitra, S., Zarka, M., Ostertag, A., Brial, F., Combes, C., Latourte, A., Bardin, T., Fenaille, F., Richette, P. and Ea, H.K.
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2025
  • 3' DRUG-seq, DRUG-seq

Integrated DRUG-Seq And Cell Painting Profiling Of JUMP MoACompounds In U2OS And HepG2 Cells

Alexandre Coudray, Andrea Hadjikyriacou, Riccardo Dainese, Daniel Alpern
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2025
  • DRUG-seq

Comprehensive 2D/3D RAS Cell Panel For Mutation-Specific Inhibitor Profiling: From Screening To Mechanistic Validation

Jack Taylor, Juliette Fernandez, Max Blanck, Anna Habryka-Pawlowska, Andrei Smid, Alix Buu Hoang, Silja Placzek, Vincent Hahaut, Luke Custerson, Hennique Erasmus, Katie Williams, Helen Pemberton, Simon Scrace and David Sorrell
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2025
  • DRUG-seq, Total DRUG-seq

Total DRUG-Seq: Cost-Efficient HTTx Platform Enabling Gene Isoforms And Non-Coding RNA Analysis For MoA Discovery And Risk Assessment

S.Placzek, M. Vallez, A. Coudray, D. Alpern, V. Hahaut
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2025
  • FLASH-seq, Single-cell FLASH-seq

Fast And Highly Sensitive Full-Length ScRNA-Seq Using FLASH-Seq

V.Hahaut, M.D. Rumper, Q. Zhou
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2025
  • DRUG-seq, Spheroid DRUG-seq

In Vitro Evaluation of the Safety and Efficacy of Cibisatamab Using Adult Stem Cell-Derived Organoids and Colorectal Cancer Spheroids.

Anstett, V.; Heinzelmann, E.; Piraino, F.; Roch, A.; Chrisnandy, A.; Norkin, M.; Garnier, V.; Homicsko, K.; Hoehnel-Ka, S.; Brandenberg, N.
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2025
  • 3' BRB-seq, BRB-seq

Targeting stemness pathways modulates macrophage polarization and reprograms the tumor microenvironment.

Austeja Butkute, Marius Baltramonaitis, Simona Malmige, Adas Darinskas, Vita Pasukoniene, Agata Mlynska.
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2021
  • 3' BRB-seq, BRB-seq

The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression.

Kaya-Çopur, A., Marchiano, F., Hein, M. Y., Alpern, D., Russeil, J., Luis, N. M., Mann, M., Deplancke, B., Habermann, B. H., & Schnorrer, F.
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2021
  • 3' BRB-seq, BRB-seq

Extensive tissue-specific expression variation and novel regulators underlying circadian behavior.

Litovchenko, M., Meireles-Filho, A. C. A., Frochaux, M. V., Bevers, R. P. J., Prunotto, A., Anduaga, A. M., Hollis, B., Gardeux, V., Braman, V. S., Russeil, J. M. C., Kadener, S., dal Peraro, M., & Deplancke, B.
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2021
  • 3' BRB-seq, BRB-seq

Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction.

Giacosa, S., Pillet, C., Séraudie, I., Guyon, L., Wallez, Y., Roelants, C., Battail, C., Evrard, B., Chalmel, F., Barette, C., Soleilhac, E., Fauvarque, M.-O., Franquet, Q., Sarrazin, C., Peilleron, N., Fiard, G., Long, J.-A., Descotes, J.-L., Cochet, C., & Filhol, O.
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2021
  • 3' BRB-seq, BRB-seq

Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma.

Christian, W. T., Tiphaine, O.-M., Nava, E., Christian, H., Federico, A. S., Jonathan, N., Dominique, C., Cécile, G., Laurence, M., Sophia, S. W., Shehnaz, K. H., Ioannis, T., Matthias, C., Andri, R., Manuel, B., Matthias, H., Patrick, S., Enos, B., Huldrych, F. G., Pejman, M., Paul, J. M., Charles, S. R., Caroline, B., & Jacques, F.
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2021
  • 3' BRB-seq, BRB-seq

LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis.

Bast-Habersbrunner, A., Kiefer, C., Weber, P., Fromme, T., Schießl, A., Schwalie, P. C., Deplancke, B., Li, Y., & Klingenspor, M.
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2020
  • 3' BRB-seq, BRB-seq

Inter-embryo gene expression variability recapitulates the hourglass pattern of evo-devo.

Liu, J., Frochaux, M., Gardeux, V., Deplancke, B., & Robinson-Rechavi, M.
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2020
  • 3' BRB-seq, BRB-seq

Mitochondrial gene signature in the prefrontal cortex for differential susceptibility to chronic stress.

Weger, M., Alpern, D., Cherix, A., Ghosal, S., Grosse, J., Russeil, J., Gruetter, R., de Kloet, E. R., Deplancke, B., & Sandi, C.
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2020
  • 3' BRB-seq, BRB-seq

Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas.

Yuan, C., Pan, Z., Zhao, K., Li, J., Sheng, Z., Yao, X., Liu, H., Zhang, X., Yang, Y., Yu, D., Zhang, Y., Xu, Y., Zhang, Z.-Y., Huang, T., Liu, W., & Ouyang, H.
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2020
  • 3' BRB-seq, BRB-seq

Cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel.

Frochaux, M. V., Bou Sleiman, M., Gardeux, V., Dainese, R., Hollis, B., Litovchenko, M., Braman, V. S., Andreani, T., Osman, D., & Deplancke, B.
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2019
  • 3' BRB-seq, BRB-seq

Sex-dependent and sex-independent regulatory systems of size variation in natural populations.

Okada, H., Yagi, R., Gardeux, V., Deplancke, B., & Hafen, E.
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2019
  • 3' BRB-seq, BRB-seq

Commensal Gut Bacteria Buffer the Impact of Host Genetic Variants on Drosophila Developmental Traits under Nutritional Stress.

Ma, D., Bou-Sleiman, M., Joncour, P., Indelicato, C.-E., Frochaux, M., Braman, V., Litovchenko, M., Storelli, G., Deplancke, B., & Leulier, F.
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2019

Systems-Genetics-Based Inference of a Core Regulatory Network Underlying White Fat Browning.

Li, Y., Schwalie, P. C., Bast-Habersbrunner, A., Mocek, S., Russeil, J., Fromme, T., Deplancke, B., & Klingenspor, M.
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2019
  • 3' BRB-seq, BRB-seq

Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel.

Bevers, R. P. J., Litovchenko, M., Kapopoulou, A., Braman, V. S., Robinson, M. R., Auwerx, J., Hollis, B., & Deplancke, B.
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