Explore publications, scientific posters, application notes, webinars, and other resources related to our technologies.
Maxine Leonardi, Yves Paychère, Felix Naef.
Alexandre Coudray, Silja Placzek, Marine Vallez, Alix Buu Hoang, Vincent Hahaut and Daniel Alpern
Elodie Koenig, Mark Ofield, Adam Peall, Elizabeth Bourne, Humberto Ferreira, Ji Hoon Han, Silja Placzek, Marine Vallez, Vincent Hahaut, Riccardo Dainese, Daniel Alpern
Yunhee Jeong, Benjamin Buer, Nicolas Arning, Tabea Schlemeyerb, Luigi Di Vierto, Alix Buu Hoang, Sven Geibel
This paper demonstrates how paired-end sequencing of multiplexed RNA-seq libraries that is currently only possible on AVITI™ systems, boosts transcript detection rate while uncovering physiologically-relevant promoter switching events.
Larissa Carvalho Costa, Christopher Gottschalk, Davis M. Upchurch, Oscar P. Hurtado-Gonzales, Ben N. Mansfeld, Alan Yocca, Lauren Whitt, Cheryl Vann, Gennaro Fazio
In this tech note, we showcase the technical performance of MERCURIUS™ 1536 DRUG-seq and suggest that this AI-ready, automatable, transcriptomic data generation technology can help AI-enabled drug discovery teams build extensive perturbation data moats that give adopters the competitive advantage needed to improve foundational model performance and experimentally assess AI-native predictions.
For the first time, 1536-well whole transcriptome profiling brings biologically rich readouts to primary screening and large-scale perturbation dataset generation.
Max Blanck, Anna Habryka-Pawlowska, Joanna Bird, David Sorrell, Silja Placzek, Vincent Hahaut
A 33-compound study demonstrating reproducible transcriptomic profiling at 1536-well scale, with gene-level resolution of mechanisms of action, toxicity pathways, and dose-dependent responses.
From One Cell to Systems Biology: How Scalable Transcriptomics Is Driving the Bold Future of Single-Cell Multi-Omics
Anstett, V.; Heinzelmann, E.; Piraino, F.; Roch, A.; Chrisnandy, A.; Norkin, M.; Garnier, V.; Homicsko, K.; Hoehnel-Ka, S.; Brandenberg, N.
Austeja Butkute, Marius Baltramonaitis, Simona Malmige, Adas Darinskas, Vita Pasukoniene, Agata Mlynska.
Akisawa Satomi, Riho Saito, Tadahaya Mizuno, Hiroki Sugishita, Hideki Ukai, Shigeyuki Shichino, Masashi Yanagisawa, Kouji Matsushima, Yukiko Gotoh, Tomohiko Okazaki.
Tarek Elmzzahi, Chun-Hsi Su, Mehrnoush Hadaddzadeh Shakiba, Doaa Hamada, DaryaMalko, Maren Koehne, Aleksej Frolov, Teisha Mason, Yuanfang Li, Rebekka Scholz, Collins Osei-Sarpong, Leonie Heyden, Jonas Schulte-Schrepping, Lorenzo Bonaguro, Kristian Haendler, Vassiliki Boussiotis, Annett Halle, Elena De Domenico, Daniel HDGray, Martin Fuhrmann, Zeinab Abdullah, Axel Kallies, Kevin Man, Marc D. Beyer.
Valentin Beauvais, Clémence Couton Nicolò Tonci, Sébastien, Limet, Lucile Mollet, Thierry Prazuck and Sophie Robert.
Wu, C., Wang, T., Ghosh, A. et al.
Pham, C.N., Castelli, F., Finet, F., Leroy, C., Chollet, C., Chirayath, T.W., Moitra, S., Zarka, M., Ostertag, A., Brial, F., Combes, C., Latourte, A., Bardin, T., Fenaille, F., Richette, P. and Ea, H.K.
V.Hahaut, M.D. Rumper, Q. Zhou
Overview of the data from MERCURIUS™ Total DRUG-seq: an early multiplexing protocol that provides full-length gene-body coverage from extraction-free RNA, enabling isoform detection, alternative promoter usage, and splicing event analysis, while maintaining high sensitivity with as few as 2’000 cells.
Jack Taylor, Juliette Fernandez, Max Blanck, Anna Habryka-Pawlowska, Andrei Smid, Alix Buu Hoang, Silja Placzek, Vincent Hahaut, Luke Custerson, Hennique Erasmus, Katie Williams, Helen Pemberton, Simon Scrace and David Sorrell
Alexandre Coudray, Andrea Hadjikyriacou, Riccardo Dainese, Daniel Alpern
Panos G. Ziros, Dionysios V. Chartoumpekis, Ilias Georgakopoulos-Soares, Georgios Psarias, Gerasimos P. Sykiotis.
Stéphanie Boder‐Pasche, Mustafa Demir, Sarah Heub, Manon Garzuel, Réal Ischer, Daniel Migliozzi, Siegfried Graf, Noa Schmid, H. Baris Atakan, Daria Gudkova, Daniel Alpern, Riccardo Dainese, Bart Deplancke, Gilles Weder
Mitra Gultom, Lin Lin, Camilla Blunk Brandt, Anastasia Milusev, Alain Despont, Jane Shaw, Yvonne Döring, Yonglun Luo, Robert Rieben.
Catherine Martin, Bertrand Evrard, Frédéric Percevault, Kate Ryder, Thomas Darde, Aurélie Lardenois, Maxim Zhadobov, Ronan Sauleau, Frédéric Chalmel, Yves Le Dréan, Denis Habauzit.
Rodrigues Sousa, E., de Brot, S., Zoni, E. et al.
Sofa Pavlou, Stefanie Foskolou, Nikolaos Patikas, Sarah F. Field, Evangelia K. Papachristou, Clive D’ Santos, Abigail R. Edwards, Kamal Kishore, Rizwan Ansari, Sandeep S. Rajan, Hugo J. R. Fernandes, Emmanouil Metzakopian.
Sheng Ying, Brandon Webster, Lina Gomez-Cano, Kiran-Kumar Shivaiah, Qianjie Wang, Linsey Newton, Erich Grotewold, Addie Thompson and Peter K. Lundquist.
Przystal, J. M., Cianciolo Cosentino, C., Yadavilli, S., Zhang, J., Laternser, S., Bonner, E. R., Prasad, R., Dawood, A. A., Lobeto, N., Chin Chong, W., Biery, M. C., Myers, C., Olson, J. M., Panditharatna, E., Kritzer, B., Mourabit, S., Vitanza, N. A., Filbin, M. G., de Iuliis, G. N., Dun, M. D., Koschmann, C., Cain, J. E., Grotzer, M. A., Waszak, S. M., Mueller, S., & Nazarian, J.
Laloli, L., Licheri, M. F., Probst, L., Licheri, M., Gultom, M., Holwerda, M., V’kovski, P., & Dijkman, R.
Mouri, K., Guo, M. H., de Boer, C. G., Lissner, M. M., Harten, I. A., Newby, G. A., DeBerg, H. A., Platt, W. F., Gentili, M., Liu, D. R., Campbell, D. J., Hacohen, N., Tewhey, R., & Ray, J. P.
Ishino, T., Takeno, S., Takemoto, K., Yamato, K., Oda, T., Nishida, M., Horibe, Y., Chikuie, N., Kono, T., Taruya, T., Hamamoto, T., & Ueda, T.
Hu, T., Todberg, T., Andersen, D., Danneskiold-Samsøe, N. B., Hansen, S. B. N., Kristiansen, K., Ewald, D. A., Brix, S., Rosa, J. C. d., Hoof, I., Skov, L., & Litman, T.
Hirai, S., Tomimatsu, K., Miyawaki-Kuwakado, A., Takizawa, Y., Komatsu, T., Tachibana, T., Fukushima, Y., Takeda, Y., Negishi, L., Kujirai, T., Koyama, M., Ohkawa, Y., & Kurumizaka, H.
Lalli, M., Yen, A., Thopte, U., Dong, F., Moudgil, A., Chen, X., Milbrandt, J., Dougherty, Joseph D., & Mitra, Robi D.
Hahaut, V., Pavlinic, D., Carbone, W et al.,
Giacosa, S., Pillet, C., Séraudie, I., Guyon, L., Wallez, Y., Roelants, C., Battail, C., Evrard, B., Chalmel, F., Barette, C., Soleilhac, E., Fauvarque, M.-O., Franquet, Q., Sarrazin, C., Peilleron, N., Fiard, G., Long, J.-A., Descotes, J.-L., Cochet, C., & Filhol, O.
Bast-Habersbrunner, A., Kiefer, C., Weber, P., Fromme, T., Schießl, A., Schwalie, P. C., Deplancke, B., Li, Y., & Klingenspor, M.
Kaya-Çopur, A., Marchiano, F., Hein, M. Y., Alpern, D., Russeil, J., Luis, N. M., Mann, M., Deplancke, B., Habermann, B. H., & Schnorrer, F.
Litovchenko, M., Meireles-Filho, A. C. A., Frochaux, M. V., Bevers, R. P. J., Prunotto, A., Anduaga, A. M., Hollis, B., Gardeux, V., Braman, V. S., Russeil, J. M. C., Kadener, S., dal Peraro, M., & Deplancke, B.
Christian, W. T., Tiphaine, O.-M., Nava, E., Christian, H., Federico, A. S., Jonathan, N., Dominique, C., Cécile, G., Laurence, M., Sophia, S. W., Shehnaz, K. H., Ioannis, T., Matthias, C., Andri, R., Manuel, B., Matthias, H., Patrick, S., Enos, B., Huldrych, F. G., Pejman, M., Paul, J. M., Charles, S. R., Caroline, B., & Jacques, F.
Frochaux, M. V., Bou Sleiman, M., Gardeux, V., Dainese, R., Hollis, B., Litovchenko, M., Braman, V. S., Andreani, T., Osman, D., & Deplancke, B.
Liu, J., Frochaux, M., Gardeux, V., Deplancke, B., & Robinson-Rechavi, M.
Weger, M., Alpern, D., Cherix, A., Ghosal, S., Grosse, J., Russeil, J., Gruetter, R., de Kloet, E. R., Deplancke, B., & Sandi, C.
Yuan, C., Pan, Z., Zhao, K., Li, J., Sheng, Z., Yao, X., Liu, H., Zhang, X., Yang, Y., Yu, D., Zhang, Y., Xu, Y., Zhang, Z.-Y., Huang, T., Liu, W., & Ouyang, H.
Bevers, R. P. J., Litovchenko, M., Kapopoulou, A., Braman, V. S., Robinson, M. R., Auwerx, J., Hollis, B., & Deplancke, B.
Okada, H., Yagi, R., Gardeux, V., Deplancke, B., & Hafen, E.
Ma, D., Bou-Sleiman, M., Joncour, P., Indelicato, C.-E., Frochaux, M., Braman, V., Litovchenko, M., Storelli, G., Deplancke, B., & Leulier, F.
Li, Y., Schwalie, P. C., Bast-Habersbrunner, A., Mocek, S., Russeil, J., Fromme, T., Deplancke, B., & Klingenspor, M.
Schwalie, P. C., Dong, H., Zachara, M., Russeil, J., Alpern, D., Akchiche, N., Caprara, C., Sun, W., Schlaudraff, K.-U., Soldati, G., Wolfrum, C., & Deplancke, B.
Tell us about your project and we will help you find the right approach.
