SERVICES

Scalable RNA sequencing tailored to your research

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Move faster, spend less, discover more

We offer a variety of scalable RNA-seq library preparation, sequencing and analysis services that combine full-transcriptome coverage with unmatched cost-efficiency and the shortest turnaround times on the market.

Whether you are looking to generate and analyze data from tens to thousands of samples, our next-generation RNA-seq technologies are designed to fit your research needs and your timeline.

Benefits

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Scalable RNA sequencing
Perform up to 384 RNA-seq library preparations in one single tube.
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Suitable to diverse sample types
From purified RNA to cell and organoid lysates, FFPE tissues, and blood or plant samples.
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Compatible with different inputs
From single cells to bulk RNA samples, our solutions accommodate a wide range of inputs.
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Flexible services

RNA-seq alone or an integrated end-to-end workflow, including cell culture and treatment, Cell Painting, NGS, and bioinformatics.
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Ideal for projects of all sizes
Scale from 48 to 10,000+ samples without sacrificing speed or data quality.
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Fast turnaround times

From samples to data in as little as two weeks to keep your projects moving forward. 

Our bulk sequencing services

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MERCURIUS™
DRUG-seq

  • RNA extraction-free
  • 3' mRNA protocol
  • Unbiased transcriptome profiling
  • Ideal for large-scale compound screening 
  • Turnaround time: from 2 weeks
Find out more
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MERCURIUS™
Total DRUG-seq

  • RNA extraction-free
  • Ultra-scalable
  • Total RNA-seq for transcriptomic profiling and target discovery
  • Turnaround time: from 3 weeks
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MERCURIUS™
Full-length
DRUG-seq

  • RNA extraction-free
  • Massively multiplexed
  • Full-length mRNA-seq
  • Turnaround time: from 3 weeks
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MERCURIUS™
Targeted
DRUG-seq

  • RNA extraction-free
  • Massively multiplexed
  • Up to 100 targets
  • Custom-developed panels
  • Turnaround time: from 8 weeks
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MERCURIUS™
Organoid
DRUG-seq

  • RNA extraction-free
  • 3' mRNA protocol
  • Unbiased transcriptome profiling
  • Ideal for large-scale compound screening 
  • Turnaround time: from 3 weeks
Find out more

Our single-cell sequencing service

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MERCURIUS™
FLASH-seq

  • RNA extraction-free
  • FACS-sorted cells
  • Ultra-sensitive
  • Plate-based
  • Turnaround time: from 4 weeks
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Get a Custom Quote

Ready to get started? Tell us about your project, and we will provide a personalized quote based on your specific needs and research goals.

Our end-to-end service approach

 

Custom data analysis & advanced visualization

Unlock deeper insights from your RNA-seq data with our tailored data analysis services.

Our preliminary data analysis can be accompanied by publication-ready visualizations such as volcano plots, clustered heatmaps, and our signature barplot wheels.

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Gene detection overview

Analysis of top DE genes -2

Analysis of top DE genes reveals signature of drug response in combinatorial treatment context

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DRUG-seq can detect potential synergistic /antagonistic effects of drug combinations

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DRUG-seq enables detailed pathway analysis of biological processes.

What do our customers say

 

 

" We would be glad to work together again"

The DRUG-seq platform enabled us to systematically profile compound-induced transcriptional responses at scale, generating a rich dataset that helped prioritize testable hypotheses. The team at Alithea provided outstanding technical guidance throughout, including support in developing a customized analysis pipeline tailored to our needs. The turnaround time was fast, the process seamless, and the collaboration highly productive. We would be glad to work together again.

Mikołaj Słabicki, Ph.D. Principal Investigator at the MGH Krantz Family Center for Cancer Research. Assistant Professor of Medicine at Harvard Medical School. Affiliate Faculty Member at the Broad Institute of MIT and Harvard

"It's fast, scalable, and incredibly cost-effective"

 

DRUG-seq has completely transformed how I approach and think about transcriptomic screening. It's fast, scalable, and incredibly cost-effective—perfect for profiling hundreds of compounds in parallel. In my experience, it’s one of the most powerful tools for uncovering mechanisms of action and capturing transcriptional signatures at scale. I've used DRUG-seq to profile different cells treated under time points, dose responses, combination treatments, and a variety of complex cellular models, from cardiomyocytes to organoids—and it consistently delivers high-quality, actionable data. The ability to pool samples early without compromising data quality truly makes it a game-changer.

 

Andrea Hadjikyriacou, Ph.D. Principal Scientist I, Novartis Biomedical Research

BRB-seq was a great way for us to multiplex large numbers of RNA samples for sequencing. We wanted a gene expression curve with a tight temporal resolution, thus, many time points for several conditions. We are very happy with the quality of the results and with the cost benefit.

Dr. Nuno Miguel Luis CNRS Researcher

...excellent method for multiplexing a large array of RNA samples for sequencing

 

BRB-seq has proven to be an excellent method for multiplexing a large array of RNA samples for sequencing. Our team sought to generate gene expression profiles to enable our research on possible neurodegeneration therapeutic targets, requiring multiple samples for various experimental conditions. The outcomes have exceeded our expectations in terms of both result quality and cost-effectiveness, leaving us thoroughly satisfied and impressed.

Dr. Emmanouil Metzakopian VP of Research and Development, bit.bio

Featured resources

Check out our blog posts for detailed insights into our services, or read our overview to get the big picture. Still unsure?

Try our Service Selection Tool to find the best fit for your project.

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Not sure which service is right for you?
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25-06-2024
Questions About our RNA-Seq Service? Look No Further!
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17-06-2025
How to Choose the Right RNA-seq Service Provider for Your Screening Study

Speak with one of our RNA experts


We’re here to support your research every step of the way by delivering high-quality and publication-ready data. Book a one-on-one call with one of our RNA experts to discover how we can assist your next project.