Alithea Genomics Blog | Riccardo Dainese

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06 Sep 2022

How does BRB-seq compare to SCRB-seq?

Novel sequencing technologies based on the 3' barcoding of mRNA now enable transcriptomic studies wi...

Written by Riccardo Dainese

Tutorials
BRB-seq
Benchmarking
SCRB-seq

26 Aug 2022

Large-scale RNA-seq series Ep. 6 – Sex Impacts Gene Expression, but not the way you think!

In 2020, the Genotype-Tissue Expression (GTEx) Consortium published seminal findings about how sex i...

Written by Riccardo Dainese

Blog
Large-scale RNA-seq series

22 Aug 2022

Large-scale RNA-seq series – Ep. 5. – Gene expression networks control organ development across species

In one of the largest studies of its kind, researchers used bulk RNA-seq to decode the gene expressi...

Written by Riccardo Dainese

Tutorials
Blog
Large-scale RNA-seq series

18 Aug 2022

Large-scale RNA-seq series – EP.3: ‘Multi-omics’ improves the classification of 33 different cancer types using 10,000 tumor samples.

In 2018 The Cancer Genome Atlas (TCGA) published groundbreaking findings from the largest ‘multi-omi...

Written by Riccardo Dainese

Blog
Large-scale RNA-seq series

16 Aug 2022

Large-scale RNA-seq series Ep. 4: BRB-seq uncovers novel features of fruit fly embryogenesis

A recent publication has used Bulk RNA Barcoding and sequencing (BRB-seq) to investigate one of the ...

Written by Riccardo Dainese

Large-scale RNA-seq series
BRB-seq

14 Aug 2022

BRB-seq in cancer therapeutics: differential gene expression elucidates the molecular mechanisms of high-grade pediatric gliomas

Diffuse midline gliomas: background and emerging therapies

Written by Riccardo Dainese

Blog
BRB-seq
Cancer therapy

08 Aug 2022

Large-scale RNA-seq series - Ep.2: Predicting cancer outcomes by estimation of tumor specific total mRNA levels in bulk RNA-seq

A recent ground-breaking study uses a mathematical approach to measure tumor-specific total mRNA lev...

Written by Riccardo Dainese

Blog
Large-scale RNA-seq series

22 Jul 2022

BRB-seq pipeline – downstream analysis best practices

In this post, we will see briefly how to perform downstream analysis for RNA-seq data.

Written by Riccardo Dainese

Tutorials
Blog
BRB-seq

21 Jul 2022

Large-scale RNA-seq series - Ep.1: RNA-seq helps uncover the genetic regulation of blood cells

The largest blood cell genotyping and transcriptomic study ever performed has shown that a much high...

Written by Riccardo Dainese

Blog
HT transcriptomics series

21 Jul 2022

COVID-19 under the BRB-Seq microscope: A Tale of Two Coronaviruses

RNA sequencing (RNA-seq) provides a molecular snapshot of the cellular transcriptome, offering a tre...

Written by Riccardo Dainese

Immunology and infectious diseases
Blog
BRB-seq
COVID

20 Jun 2022

How do BRB-seq pre-processing results look like?

In this post, we will see briefly how BRB-seq libraries are processed, and what are the output files...

Written by Riccardo Dainese

Tutorials
BRB-seq

07 Jun 2022

BRB-seq vs Truseq

Despite its widespread use, RNA-seq is still too laborious and expensive to replace RT-qPCR as the d...

Written by Riccardo Dainese

Blog
BRB-seq
Benchmarking

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Cells and organoids (Extraction-free)

Purified RNA

Accessories

Cells and Organoids (EXTRACTION-FREE)

PURIFIED RNA

Whole Blood RNA

Cells and organoids (Extraction-free)

Purified RNA

Accessories

Cells and Organoids (EXTRACTION-FREE)

PURIFIED RNA

Whole Blood RNA

Blog & tutorials

How does BRB-seq compare to SCRB-seq?

Large-scale RNA-seq series Ep. 6 – Sex Impacts Gene Expression, but not the way you think!

Large-scale RNA-seq series – Ep. 5. – Gene expression networks control organ development across species

Large-scale RNA-seq series – EP.3: ‘Multi-omics’ improves the classification of 33 different cancer types using 10,000 tumor samples.

Large-scale RNA-seq series Ep. 4: BRB-seq uncovers novel features of fruit fly embryogenesis

BRB-seq in cancer therapeutics: differential gene expression elucidates the molecular mechanisms of high-grade pediatric gliomas

Large-scale RNA-seq series - Ep.2: Predicting cancer outcomes by estimation of tumor specific total mRNA levels in bulk RNA-seq

BRB-seq pipeline – downstream analysis best practices

Large-scale RNA-seq series - Ep.1: RNA-seq helps uncover the genetic regulation of blood cells

COVID-19 under the BRB-Seq microscope: A Tale of Two Coronaviruses

How do BRB-seq pre-processing results look like?

BRB-seq vs Truseq

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